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KMID : 1103920090150040517
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Korean Journal of Hepatology
2009 Volume.15 No. 4 p.517 ~ p.523
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A case of acute cholestatic hepatitis induced by Corydalis speciosa Max.
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Kang Hyun-Seok
Lee Yoon-Taek
Yun Tae-Jung
Lee Kwang-Gyun
Seo Yeon-Seok
Yeon Jong-Eun
Byun Kwan-Soo
Um Soon-Ho
Kim Chang-Duck
Ryu Ho-Sang
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Abstract
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Herbs are widely used as treatments for various symptoms. However, several herbs have been reported to be inducers of liver injury. We report herein a case of hepatotoxicity induced by Corydalis speciosa Max. A 37-year-old male complained of jaundice and mild abdominal discomfort. A thorough history was taken, and laboratory investigation, diagnostic imaging studies, and percutaneous liver biopsy sampling were conducted to determine the cause of liver injury. An accurate cause was not revealed. We administered supportive management for acute cholestatic hepatitis of unknown origin, after which his symptoms disappeared and serum aminotransferase levels decreased gradually to near normal levels. However, at 2 months after discharge, the symptoms and the elevation of aminotransferase levels recurred. At that time he told us that he had repeatedly but unintentionally eaten a herb called “Hwang-geun cho”(Corydalis speciosa Max.). Thus, we diagnosed his case as herbal hepatotoxicity.
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KEYWORD
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Hepatitis Toxic, Plants Medicinal, Cholestasis Intrahepatic, Biopsy Needle
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